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. 2015 Aug 7;38(9):796–805. doi: 10.14348/molcells.2015.0116

Fig. 5.

Fig. 5.

Effect of gintonin (GT; 25 or 50 mg/kg, p.o.) on cholinergic system changes. (A) Experimental schedule to evaluate the long-term effect of gintonin on cholinergic system impairment in the APPswe/PSEN-1 double Tg mouse. (B) Acetylcholine level, (C) acetylcholinesterase activity, and choline acetyltransferase activity in the hippocampus of the APPswe/PSEN-1 double Tg mouse. Donepezil (DPZ; 1 mg/kg, i.p.) was used as a reference drug. Sal = saline. Each value is the mean ± S.E.M of four mice. #P < 0.05, ##P < 0.01 vs. Sal (one-way ANOVA followed by Fisher’s PLSD test).