Table 4.
Top 25 (Log-Ratio) Up- and Down-Regulated Transcripts in BxPC3 8–24 Hours After SMAD4 Expression
| Gene ID | P Value | Log-Ratio | Accession |
|---|---|---|---|
| LOC100128765 | 4.06E-05 | −2.934 | XM_001723069.1 |
| MNS1 | 9.02E-06 | −2.575 | NM_018365.1 |
| OSBP2 | 1.33E-04 | −2.439 | NM_030758.3 |
| TRAF1 | 1.30E-13 | −2.331 | NM_005658.3 |
| SPINK4 | 3.64E-11 | −2.204 | NM_014471.1 |
| KIF24 | 1.66E-06 | −2.166 | NM_194313.2 |
| CENPI | 2.61E-08 | −2.165 | NM_006733.2 |
| AOX1 | 2.20E-05 | −2.044 | NM_001159.3 |
| PKMYT1 | 6.44E-07 | −2.021 | NM_182687.1 |
| C15ORF42 | 1.72E-02 | −2.000 | NM_152259.3 |
| UBE2C | 2.16E-09 | −1.902 | NM_181799.1 |
| ESM1 | 8.66E-22 | −1.853 | NM_007036.3 |
| CASC5 | 1.89E-07 | −1.842 | NM_144508.3 |
| ACYP1 | 3.80E-05 | −1.841 | NM_203488.1 |
| MKI67 | 5.31E-06 | −1.836 | NM_002417.3 |
| IL1RL1 | 4.65E-20 | −1.821 | NM_003856.2 |
| TNIK | 1.05E-03 | −1.778 | NM_015028.1 |
| TFF1 | 3.02E-04 | −1.745 | NM_003225.2 |
| BIRC5 | 2.62E-08 | −1.739 | NM_001012271.1 |
| SH2D5 | 2.09E-04 | −1.727 | XM_375698.3 |
| ESPL1 | 1.34E-07 | −1.721 | NM_012291.4 |
| NCAPG | 3.62E-22 | −1.708 | NM_022346.3 |
| LOC81691 | 1.57E-05 | −1.633 | NM_030941.1 |
| IL1R2 | 4.41E-04 | −1.613 | NM_173343.1 |
| PIF1 | 4.67E-08 | −1.610 | NM_025049.2 |
| LOC646743 | 3.45E-04 | 6.573 | XM_929693.1 |
| BMF | 3.68E-38 | 6.024 | NM_033503.3 |
| KRT81 | 6.66E-16 | 4.201 | NM_002281.2 |
| CDH15 | 3.68E-38 | 3.951 | NM_004933.2 |
| LOC644023 | 7.60E-04 | 3.502 | XM_937657.1 |
| CGB7 | 3.68E-38 | 3.441 | NM_033142.1 |
| DPP6 | 2.03E-08 | 3.354 | NM_001039350.1 |
| CGB | 3.68E-38 | 3.333 | NM_000737.2 |
| LHB | 3.68E-38 | 3.170 | NM_000894.2 |
| SNCG | 3.80E-07 | 3.138 | NM_003087.1 |
| LOXL4 | 3.68E-38 | 3.125 | NM_032211.6 |
| CGB5 | 3.68E-38 | 3.122 | NM_033043.1 |
| TP53INP1 | 2.49E-12 | 3.047 | NM_033285.2 |
| CGB8 | 3.68E-38 | 3.023 | NM_033183.2 |
| ZNF750 | 9.81E-09 | 2.996 | NM_024702.2 |
| LOC339352 | 1.15E-04 | 2.985 | XR_019601.2 |
| DBP | 1.38E-11 | 2.921 | NM_001352.2 |
| LOC642749 | 6.64E-09 | 2.843 | XM_931058.1 |
| TMEM140 | 3.01E-11 | 2.775 | NM_018295.2 |
| MMP7 | 3.68E-38 | 2.765 | NM_002423.3 |
| CLIC3 | 3.68E-38 | 2.677 | NM_004669.2 |
| MAMDC2 | 3.68E-38 | 2.620 | NM_153267.3 |
| LOC645732 | 2.29E-04 | 2.619 | XM_928743.1 |
| HS.576106 | 3.27E-09 | 2.605 | AK097377 |
| WIPI1 | 3.68E-38 | 2.573 | NM_017983.4 |
Most dramatically regulated genes between 8 and 24 hours after SMAD4 expression. Transcripts with a signal of greater than 50 in the pairwise comparison that showed more than or equal to 2-fold change in expression with a P < .05 are included sorted by log-ratio to include the top 25 down- and up-regulated transcripts.