TABLE 2.
Characteristics of participants in the incident adenoma and recurrent adenoma data set by case status
| Incident adenoma |
Recurrent adenoma |
|||||
| Characteristic | Cases(n = 1004) | Noncases(n = 15,976) | P value | Cases (n = 738) | Noncases (n = 929) | P value |
| Total fiber intake, g/1000 kcal | 11.2 ± 3.51 | 12.0 ± 3.6 | <0.001 | 11.1 ± 3.4 | 11.2 ± 3.5 | 0.50 |
| Age at diagnosis or endoscopy, y | 66.6 ± 5.0 | 66.7 ± 4.9 | 0.62 | 66.9 ± 5.3 | 68.2 ± 5.4 | <0.001 |
| Male sex, n (%) | 665 (66.2) | 8756 (54.8) | <0.001 | 535 (72.5) | 570 (61.4) | <0.001 |
| Ethnicity, n (%) | 0.02 | 0.001 | ||||
| Non-Hispanic white | 910 (90.6) | 14,181 (88.8) | 689 (93.4) | 887 (95.5) | ||
| Non-Hispanic black | 36 (3.6) | 461 (2.9) | 14 (1.9) | 27 (2.9) | ||
| Asian | 42 (4.2) | 957 (6.0) | 15 (2.0) | 4 (0.4) | ||
| Other | 16 (1.6) | 377 (2.4) | 20 (2.7) | 11 (1.2) | ||
| Education | ||||||
| College graduate or postgraduate, n (%) | 389 (38.9) | 6266 (39.3) | 0.89 | 282 (38.4) | 325 (35.0) | 0.51 |
| BMI, kg/m2 | 27.7 ± 4.7 | 27.1 ± 4.6 | <0.001 | 27.8 ± 4.2 | 27.5 ± 4.5 | 0.15 |
| Physical activity ≥4 h/wk, n (%) | 229 (22.8) | 4167 (26.1) | <0.001 | 168 (22.8) | 212 (22.8) | 0.38 |
| Hormone replacement therapy use, n (%)2 | 0.09 | 0.97 | ||||
| Never | 130 (38.4) | 2291 (31.7) | 81 (39.9) | 145 (40.4) | ||
| Former | 46 (13.6) | 1072 (14.9) | 27 (13.3) | 52 (14.5) | ||
| Current | 161 (47.5) | 3816 (52.9) | 94 (46.3) | 160 (44.6) | ||
| Smoking status, n (%) | <0.001 | 0.001 | ||||
| Never | 392 (39.0) | 7854 (49.2) | 205 (27.8) | 309 (33.3) | ||
| Former | 469 (46.7) | 6521 (40.8) | 386 (52.3) | 459 (49.5) | ||
| Current | 100 (10.0) | 810 (5.1) | 96 (13.0) | 131 (14.1) | ||
| Pipe or cigar smoker only | 43 (4.3) | 786 (4.9) | 51 (6.9) | 29 (3.1) | ||
| Alcohol intake, g/d | 14.8 ± 29.8 | 10.2 ± 21.9 | <0.001 | 17.2 ± 29.5 | 14.8 ± 29.7 | 0.11 |
| Family history of colorectal cancer, n (%) | 93 (9.3) | 1367 (8.6) | 0.71 | 99 (13.5) | 123 (13.4) | 0.73 |
| Ever regular NSAID3 use, n (%) | 600 (59.8) | 9602 (60.1) | 0.59 | 412 (55.8) | 552 (59.4) | 0.14 |
| Total energy intake, kcal/d | 2182.8 ± 824.8 | 2077.6 ± 796.6 | <0.001 | 2169.0 ± 813.0 | 2098.5 ± 795.8 | 0.08 |
| Dietary calcium intake, mg/1000 kcal | 452.5 ± 156.8 | 473.4 ± 164.4 | <0.001 | 443.8 ± 148.3 | 468.5 ± 175.1 | 0.002 |
| Supplemental calcium intake, mg/d | 223.9 ± 332.2 | 277.1 ± 375.8 | <0.001 | 165.9 ± 297.8 | 216.9 ± 327.0 | 0.001 |
| Dietary folate intake, μg/1000 kcal | 179.7 ± 62.0 | 190.5 ± 64.9 | <0.001 | 177.6 ± 58.9 | 181.8 ± 67.8 | 0.19 |
| Supplemental folic acid intake, μg/d | 211.6 ± 304.9 | 240.1 ± 307.5 | 0.004 | 172.3 ± 265.4 | 203.4 ± 274.1 | 0.02 |
| Red meat intake, g/1000 kcal | 30.3 ± 18.7 | 27.9 ± 18.4 | <0.001 | 31.0 ± 17.7 | 29.4 ± 18.2 | 0.07 |
| Processed meat intake, g/1000 kcal | 6.8 ± 7.1 | 5.8 ± 6.5 | <0.001 | 7.1 ± 7.1 | 6.5 ± 6.7 | 0.05 |
1
Mean ± SD (all such values).
2
In females only.
3
NSAID, nonsteroidal anti-inflammatory drug.