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Some sesquiterpene lactones dereplicated from extracts with dual inhibition property against COX-1 and 5-LOX (stereochemistry was not shown due to the possibility of occurrence of isomers/epimers, except for tagitinin F which was confirmed through co-elution and MS/MS fragmentation of a reference standard; Figure 8). Although it should be taken into account that all STLs from the tribes investigated herein (and those shown below) must have α,β orientation at C6/C7.
