Figure 2.

Klf11 genetic deletion does not affect body weight, activity, or energy expenditure when mice are fed with normal diet. Klf11+/+ and Klf11−/− female mice were subjected to CLAMS measurements to monitor their energetic status. Body weight (A) and total body composition (B) were measured by MRI before introducing the mice into the metabolic cages. Food intake was measured (C), and food intake/body weight (D) was calculated from A and C. Total activity (E), ambulation (F), rearing (G), heat production (H), metabolic rate (I), VO₂ (J), VCO₂ (K), and respiratory coefficient (L) were measured in the mice over a 24-hour period that included day and night under feeding conditions. Each group consisted of 8 mice (*, P < .05, t test).