Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 May 27;4(10):e1040214. doi: 10.1080/2162402X.2015.1040214

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Taylor & Francis Group, LLC

PMC Copyright notice

Figure 6. — Recruitment and activation of NK cells in B16 metastases-bearing lungs of mice treated with CpG-ODN/Poly(I:C) aerosol combined with dacarbazine. Percentage and representative dot plots of NK cells, evaluated as DX5⁺ cells gated on FSClowSSClowCD45+CD3- cells (A), and of CD69+ (B) and NKG2D+ (C) NK cells, gated on DX5+ cells, obtained by enzymatic digestion of B16 metastases-bearing lungs of mice (4 mice/group) treated with aerosol CpG-ODN/Poly(I:C), DTIC, aerosol CpG-ODN/Poly(I:C) plus DTIC or left untreated. Percentage and representative dot plots of degranulating NK cells, evaluated as CD107a+ cells gated on CD45+CD3-DX5+ cells, after co-culture with B16 melanoma cells (D), and of CFSE-labeled B16 dead cells, evaluated as 7AAD+ cells gated on CFSE+ cells, after co-culture with cells obtained from lung enzymatic digestion (E). *p < 0.05, ***p < 0.001.