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IFN signature genes are not upregulated in the peripheral blood of AAD patients. Real-time qPCR was used to determine the relative mRNA expression of 5 selected ISGs in isolated CD4+ T cells. The IFN score for each patient (n=15) and control (n=15) was calculated as described in the Materials and Methods section. The bars display the mean for the whole group. ISGs, interferon-stimulated genes.
