Table 1.
Patient | Age | Underlying disease | Diagnosis at admission | Type of infection | Treatment (duration, days) | Outcomed | |
---|---|---|---|---|---|---|---|
Initial | Definitive | ||||||
Case#1 | 3 moa | Pierre Robin Syndrome | Septic shock (A. baumannii BSI) | BSI | RIF + COL (5) | VAN + COL + MEM (12) | Late relapse (UTI) Cured |
Case#2 | 21 ys | Spastic tetraparesis; dysphagia | Respiratory failureb | VAP & BSI | RIF + COL (5) | VAN + COL + MEM (15) | Cured |
Case#3 | 25 ys | Spastic tetraparesis | Respiratory failureb | BSI | VAN + COL + MEM (16) | VAN + COL + MEMc | Cured |
Case#4 | 6 mo | None | ARDS | VAP | VAN + COL + MEM (19) | VAN + COL + MEMc | Cured |
COL colistin, VAN vancomycin, RIF rifampin, MEM meropenem, UTI urinary Tract Infection, BSI bloodstream infection, VAP Ventilator-Acquired Pneumonia, ARDS Acute Respiratory Distress Syndrome
(a): Case-index; (b): caused by the underlying disease; (c): in cases #3-4 the initial therapy was the definitive one; (d): at least 3-months follow-up