Table 6. ¹⁸FDG uptake analysis from whole brain and brain regions of ADAR2 transgenic (TG) and control littermates (WT).

Wilcoxon rank-sum exact test was used to compare the brain region variables between control and transgenic mice (n=4/genotype, *p-value from Wilcoxon rank-sum exact test). Brain CT= Brain cortex, RSTR= Right striatum, LSTR= left striatum, CTX= cortex, RHIP= Right hippocampus, LHIP= Left hippocampus, THA= Thalamus, CB= Cerebellum, BFS=Basal forebrain septum, HYP= Hypothalamus, RAMY=Right amygdala, LAMY=Left amygdala, BS=Brain stem, CG=cingulated gyrus, SC=superior colliculi, OLF= olfactory bulb, RMID= right mid brain, LMID=Left mid brain, LIC=left inferior coleculi and RIC=Right inferior coleculi. TG=transgenic and WT=wild type control littermates.

Variable	Genotype	Mean	Std Dev	p- value*
Brain CT	TG	2.21	0.49	0.114
	WT	1.67	0.20
RSTR	TG	2.70	0.64	0.057
	WT	1.96	0.27
LSTR	TG	2.65	0.56	0.057
	WT	1.96	0.27
CTX	TG	2.35	0.43	0.200
	WT	1.93	0.28
RHIP	TG	2.43	0.55	0.029
	WT	1.78	0.21
LHIP	TG	2.43	0.57	0.114
	WT	1.85	0.28
THA	TG	2.57	0.49	0.114
	WT	1.96	0.29
CB	TG	2.54	0.57	0.200
	WT	2.02	0.28
BFS	TG	2.22	0.50	0.200
	WT	1.71	0.29
HYP	TG	2.25	0.56	0.029
	WT	1.45	0.22
RAMY	TG	2.09	0.53	0.200
	WT	1.44	0.38
LAMY	TG	2.10	0.56	0.114
	WT	1.44	0.29
BS	TG	2.52	0.55	0.029
	WT	1.73	0.11
CG	TG	2.47	0.57	0.200
	WT	1.86	0.29
SC	TG	2.45	0.50	0.200
	WT	1.91	0.32
OLF	TG	2.28	0.31	0.343
	WT	1.93	0.24
RMID	TG	2.54	0.64	0.029
	WT	1.71	0.22
LMID	TG	2.61	0.65	0.029
	WT	1.84	0.23
RIC	TG	2.30	0.49	0.200
	WT	1.88	0.28
LIC	TG	2.54	0.57	0.114
	WT	1.93	0.24

^*p-value from Wilcoxon rank-sum exact test