Table 2.

Predictors of vulvar cancer-specific mortality.

	Hazard ratio (95% CI)	p-value
Age at diagnosis-category		0.0046
65–74 years olda	1.0
75–84 years old	0.38 (0.18, 0.84)
85+ years old	1.79 (0.78, 4.09)
Stage		0.0009
Ia	1.0
II	0.85 (0.31, 2.34)
III	0.62 (0.20, 1.94)
IV	3.17 (1.14, 8.80)
Lymph node involvement		< 0.0001
Nonea	1.0
Lymph node involvement	7.47 (3.09, 18.04)
Surgery performed		< 0.0001
Radical vulvectomy onlya	1.0
Local excision only	3.77 (0.75, 18.85)
Unilateral or bilateral inguinal LND	12.77 (2.52, 64.64)
Radical vulvectomy + inguinal LND	2.08 (0.49, 8.83)
Adjuvant therapy		<0.0001
Nonea	1.0
Chemo or radiation therapy only	59.86 (19.21,186.54)
Chemo and radiation therapy	0.84 (0.36, 2.00)

^aReference group.