Table 1.

Serum Levels of Hormones and Cytokines of Wild-Type and Selenocysteine Lyase Knockout Mice Fed a High-Fat Diet for 4 Months

Hormone/cytokine	WT	Scly KO	p-Value (S)	p-Value (MW)
Insulin (ng/ml)	3.564 ± 1.032 (n = 9)	7.616 ± 0.8399 (n = 9)	0.0077	0.0056
Leptin (ng/ml)	16.51 ± 2.341 (n = 9)	33.20 ± 1.063 (n = 9)	<0.0001	<0.0001
Adiponectin (ng/ml)	35.07 ± 3.394 (n = 11)	29.82 ± 2.260 (n = 11)	0.2126	0.2934
Testosterone (ng/ml)	2.047 ± 1.031 (n = 6)	1.919 ± 0.7429 (n = 5)	0.9251	0.6623
TNFalpha (pg/ml)	6.240 ± 0.7822 (n = 7)	5.660 ± 1.125 (n = 10)	0.6108	0.8833
MCP1 (pg/ml)	2.371 ± 0.1081 (n = 8)	2.425 ± 0.08313 (n = 8)	0.5396	0.9015
IL-6 (pg/ml)	8.115 ± 2.281 (n = 10)	6.788 ± 2.786 (n = 11)	0.8719	0.7498

Values are mean ± SEM. Average comparison by two-tailed Student's t-test (S) and nonparametric Mann–Whitney U test (MW). p-Values under 0.05 are deemed significant and highlighted in italic/bold.

IL-6, interleukin 6; MCP1, monocyte chemotactic protein 1; TNFalpha, tumor necrosis factor alpha; WT, wild type.