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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Kidney Int. 2015 Jun 10;88(4):722–733. doi: 10.1038/ki.2015.162

Figure 7. Selective TNF-α depletion in macrophages reduces macrophage recruitment and histological changes in diabetic mice.

Figure 7

A) Immunohistochemical staining for Mac-2 positive macrophages in glomeruli and PAS-stained sections after 12 weeks of STZ-induced type 1 diabetes. Images are representative of 7-12 mice in each group. B) Summary data for macrophages/glomerulus. C) Summary data for glomerular PAS score. Data are presented as mean ± SEM. *p<0.01 compared to normal; #p<0.05 compared to diabetes TNF-αFlox/Flox. Scale bar: 10 μm.