Figure 2. Genetic and biochemical interactions between known cystoproteins.
Genetic and/or biochemical interactions are shown as solid lines. The murine cystoproteins shaded in grey (Aqp11, Bicc1, Taz) represent those where a human PKD phenotype has not yet been reported123, 192, 193. Biochemical interactions between PC1 and NPHP1 and BBS1 have been reported194, 195.