Table 3. Predictors of each QLQ-C30, QLQ-BR23, and SF-36 subscale after surgery over a 2-year period # .
QLQ-C30 | QLQ-BR23 | SF-36 | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Predictors | GQOL | PF | RF | EF | CF | SF | BI | SF | SE | FP | PCS | MCS |
Time | ||||||||||||
6th month vs. baseline | 14.20** | 20.03** | 18.32** | 24.69** | 26.53** | 10.05* | 23.21** | 10.24** | 12.79** | 17.54** | 5.67** | 5.07** |
1st year vs. baseline | 19.04** | 32.59** | 30.82** | 38.80** | 36.28** | 16.73** | 35.43** | 18.14** | 26.61** | 24.39** | 9.89** | 10.64**` |
2nd year vs. baseline | 26.59** | 46.69** | 41.64** | 44.01** | 40.37** | 24.36** | 46.15** | 19.97** | 29.86** | 31.36** | 12.82** | 11.69** |
Surgical type | ||||||||||||
MRM vs. BCS | -1.49 | -1.18 | -3.76* | -3.98** | -5.15** | 0.74 | -5.39** | 1.90 | -0.20 | 0.43 | -0.46 | -2.48* |
TRAM vs. BCS | 1.36 | 4.67* | 2.62 | 5.86** | 2.98 | 0.21 | -2.95* | 3.39* | 3.24* | 1.06 | 3.24* | 3.49* |
Age | -0.23** | -0.03 | -0.02 | -0.14* | -0.02 | -0.04 | -0.42* | -0.28** | -0.29** | -0.17* | -0.07 | -0.12* |
CCI score | -0.07* | -0.08* | -0.08* | -0.10** | -0.09* | -0.03 | -0.11** | -0.09* | -0.07* | -0.09* | -0.07* | -0.10** |
Tumor stage | ||||||||||||
Stage III/IV vs. stage 0/I | -0.12* | -0.24** | -0.22** | -0.28** | -0.30** | -0.11 | -0.25** | -0.14* | -0.14* | -0.18* | -0.18* | -0.24** |
Stage II vs. stage 0/I | -0.04 | -0.06 | -0.06 | -0.05 | -0.09* | -0.02 | -0.08* | -0.03 | -0.04 | -0.04 | -0.03 | -0.01 |
Chemotherapy | ||||||||||||
Yes vs. no | -4.91* | -4.63* | -0.52 | -3.20* | 1.32 | 0.78 | -4.10* | -1.68 | -1.56 | -6.45** | -3.57* | -2.45* |
Radiotherapy | ||||||||||||
Yes vs. no | 3.62* | -1.56 | 1.63 | 3.57* | -1.12 | 2.01 | 5.29** | 2.84 | -1.41 | 4.74* | -1.03 | 1.03 |
Hormone therapy | ||||||||||||
Yes vs. no | 3.68* | 0.57 | 1.68 | -0.68 | -0.82 | 0.94 | 4.52** | 2.13 | 1.75 | 3.93* | 0.34 | 1.08 |
Post-operative LOS | -0.03 | -0.06* | -0.09** | -0.12** | -0.18** | -0.02 | -0.14** | -0.11** | -0.06* | -0.04 | -0.07* | -0.08* |
Preoperative QOL scores | 0.39** | 0.50** | 0.61** | 0.64** | 0.57** | 0.44** | 0.48** | 0.31** | 0.42** | 0.54** | 0.48** | 0.55** |
#Values expressed as coefficients.
GQOL = global quality of life, PF = physical functioning, RF = role functioning, EF = emotional functioning, CF = cognitive functioning, SF = social functioning, BI = body image, SF = sexual functioning, SE = sexual enjoyment, FP = future perception, PCS = physical component summary, MCS = mental component summary, BCS = breast conserving surgery, MRM = modified radical mastectomy, TRAM = transverse rectus abdominis myocutaneous flap surgery (mastectomy with reconstruction), CCI = Charlson co-morbidity index, LOS = length of stay, QOL = quality of life.
*P<0.05,
**P<0.01