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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Stroke. 2015 Sep 3;46(10):2881–2885. doi: 10.1161/STROKEAHA.115.009463

Table 3.

Stratified analysis by WHR for the association between leptin* and incident any and ischemic stroke (IS) **

Top Quartile of WHR Bottom 3 quartiles of WHR
Stroke IS Stroke IS
Model n HR [CI] (p-value) n HR [CI] (p-value) n HR [CI] (p-value) n HR [CI] (p-value)
Model 1 31/189 0.64 [0.45, 0.92] (0.01) 27/189 0.65 [0.44, 0.95] (0.02) 87/564 1.02 [0.82, 1.28] (0.84) 71/564 1.03 [0.80, 1.32] (0.82)
Model 2 31/189 0.64 [0.43, 0.95] (0.02) 27/189 0.61 [0.39, 0.95] (0.02) 87/564 0.98 [0.77, 1.25] (0.89) 71/564 0.96 [0.74, 1.26] (0.78)
*

Sex-standardized natural logarithm of leptin;

**

Using an indicator of top sex-specific quartile.

HR: Hazard ratio; CI: Confidence interval; WHR: Weight-to-hip ratio;

Model 1: adjusted for age and sex; Model2: Model 1 plus systolic blood pressure, smoking, diabetes mellitus, Anti-hypertensive treatment, prevalent cardiovascular disease.