Table 3.
| N (case/controls) | MAF(case/control) | Dominant model | Additive model | Recessive model | ||||
|---|---|---|---|---|---|---|---|---|
| p-value | OR (95%CI) | p-value | OR (95%(CI) | p-value | OR (95% CI) | |||
| All Subjects | 1559/1332 | 0.30/0.22 | 0.31 | 1.09(0.92, 1.29) | 0.18 | 1.1(0.96,1.25) | 0.2 | 1.25(0.89,1.76) |
| Subjects with 0 or 1 APOL1 G1 or G2 allele | 849/1139 | 0.21/0.19 | 0.38 | 1.09(0.90,1.32) | 0.13 | 1.14(0.96,1.35) | 0.022 | 1.83(1.09,3.08) |
| Subjects with 0 APOL1 G1 or G2 allele | 374/562 | 0.11/0.12 | 0.24 | 0.81(0.58,1.15) | 0.40 | 0.87(0.64,1.20) | 0.41 | 1.6(0.52,4.90) |
| Subjects with 1 APOL1 G1 or G2 allele | 463/574 | 0.28/0.26 | 0.38 | 1.12(0.87,1.45) | 0.15 | 1.17(0.94,1.46) | 0.064 | 1.75(0.97,3.18) |
| Subjects with 2 APOL1 G1 or G2 allele | 722/196 | 0.40/0.40 | 0.64 | 1.08(0.78,1.50) | 0.79 | 1.03(0.82,1.30) | 0.92 | 0.98(0.64,1.50) |
| Subjects with 1 G1 allele | 166/219 | 0.26/0.21 | 0.09 | 1.46(0.95,2.25) | 0.084 | 1.41(0.96,2.08) | 0.49 | 1.55(0.44,5.46) |
| Subjects with 1 G2 allele | 297/355 | 0.30/0.28 | 0.75 | 0.95(0.70,1.31) | 0.69 | 1.06(0.81,1.37) | 0.10 | 1.76(0.90,3.46) |
P-values not adjusted for multiple comparisons
OR, odds ratio