Table 1.
Demographic and Neuroimaging data.
Variable | North American Ischemic Stroke Cohort (N=61) | South Korean Ischemic Stroke Cohort (N=45) | p-value |
---|---|---|---|
Men/Women | 34/27 | 21/24 | 0.4 |
Age (years) | 64.3 ± 12.4 | 63.2 ± 14.0 | 0.7 |
Years of education | 14.7 ± 3.1 | 9.3 ± 4.7 | <0.0001 |
Days between stroke onset and neuropsychological testing | 422.6 ± 246.1 | 101.7 ± 19.1 | <0.0001 |
MMSE | 27.8 ± 2.3 | 24.6 ± 4.6 | <0.0001 |
NIHSS at neuropsychological testing | 1.7 ± 2.2 | 1.2 ± 2.1 | 0.04 |
TMT-A (s) | 55.4 ± 32.2 | 58.0 ± 59.2 | 0.2 |
TMT-B (s) | 144.0 ± 81.3 | 140.4 ± 115.5 | 0.1 |
TMT-B-A difference score | 88.0 ± 63.4 | 82.4 ± 83.6 | 0.08 |
TMT-B-A proportion score | 1.69 ± 1.05 | 1.65 ± 1.71 | 0.06 |
TMT-B-A quotient score | 2.69 ± 1.05 | 2.65 ± 1.71 | 0.06 |
CHIPS | 22.4 ± 15.5 | 13.4 ± 11.2 | 0.001 |
SLF stroke involvement | 53% (n=32) | 24% (n=11) | 0.004 |
Executive network stroke involvement | 69% (n=43) | 67% (n=30) | 0.7 |
Total Infarction (%)† | 2.3 ± 3.7 | 0.71 ± 1.5 | 0.004 |
WMH (%)† | 0.84 ± 1.08 | 0.36 ± 0.44 | <0.0001 |
NAGM (%)† | 42.8 ± 3.3 | 45.9 ± 5.9 | 0.001 |
NAWM (%)† | 32.3 ± 3.8 | 33.7 ± 5.0 | 0.1 |
vCSF (%)† | 3.2 ± 1.6 | 2.3 ± 1.3 | 0.001 |
sCSF (%)† | 18.5 ± 3.9 | 17.0 ± 2.8 | 0.03 |
Mean ± SD
Volumes expressed as a percentage of Total Intracranial Volume for head size correction
Abbreviations:
National Institute of Health Stroke Scale (NIHSS);Mini-mental State Examination (MMSE); Trail Making Test (TMT); White Matter Hyperintensities (WMH); Normal appearing grey matter (NAGM); Normal appearing white matter (NAWM); ventricular cerebrospinal fluid volume (vCSF); sulcal cerebrospinal fluid volume (sCSF); Cholinergic Hyperintensities Projections Scale (CHIPS); Superior Longitudinal Fasciculus (SLF)