Table 3.
Unstandardised coefficients from linear regressions of metabolic factors and EM and EMRA T cell numbers
| Variables | EM (CD27−CD45RA−) | EMRA (CD27−CD45RA+) | ||||
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | Model 1 | Model 2 | Model 3 | |
| All participants (n = 1,103) | ||||||
| HbA1c | 2.03 (0.58)*** | 1.87 (0.59)*** | 1.54 (0.59)* | 2.20 (0.77)** | 2.05 (0.77)** | 1.68 (0.78)* |
| Fasting glucose | 2.15 (2.06) | 2.31 (2.06) | 3.23 (2.07) | −2.92 (2.69) | −2.74 (2.70) | −1.72 (2.73) |
| Cholesterol | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.02 (0.01) |
| LDL-C | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) |
| HDL-C | −0.13 (0.05)** | −0.13 (0.05)** | −0.06 (0.05) | −0.16 (0.06)** | −0.15 (0.06)* | −0.08 (0.06) |
| LDL-C/HDL-C | 0.20 (0.07)** | 0.20 (0.07)** | 0.14 (0.07)* | 0.21 (0.09)* | 0.21 (0.09)* | 0.13 (0.10) |
| Triacylglycerol | 0.14 (0.05)** | 0.13 (0.05)** | 0.11 (0.05)* | 0.21 (0.07)** | 0.20 (0.07)** | 0.18 (0.07)* |
| CMV negative (n = 703) | ||||||
| HbA1c | 0.97 (0.65) | 0.86 (0.65) | 0.46 (0.66) | 0.87 (0.23) | 0.94 (0.82) | 0.48 (0.84) |
| Fasting glucose | 2.34 (2.18) | 2.40 (2.18) | 3.75 (2.23) | −1.3 (2.77) | −1.29 (2.77) | 0.36 (2.84) |
| Cholesterol | 0.00 (0.01) | 0.00 (0.01) | 0.00 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) |
| LDL-C | 0.00 (0.01) | 0.01 (0.01) | 0.00 (0.01) | 0.01 (0.01) | 0.01 (0.01) | 0.01 (0.01) |
| HDL-C | −0.09 (0.05) | −0.08 (0.05) | −0.03 (0.05) | −0.02 (0.06) | −0.03 (0.06) | 0.02 (0.07) |
| LDL-C/HDL-C | 0.11 (0.07) | 0.12 (0.07) | 0.06 (0.08) | 0.08 (0.09) | 0.09 (0.09) | 0.01 (0.10) |
| Triacylglycerol | 0.07 (0.06) | 0.06 (0.06) | 0.03 (0.06) | 0.12 (0.07) | 0.13 (0.07) | 0.09 (0.07) |
| CMV positive (n = 400) | ||||||
| HbA1c | 3.11 (1.03)** | 3.02 (1.03)** | 2.75 (1.03)** | 3.02 (1.00)** | 2.92 (1.01)** | 2.90 (1.02)** |
| Fasting glucose | 2.41 (3.82) | 2.19 (3.83) | 2.36 (3.83) | −3.86 (3.72) | −3.78 (3.74) | −3.40 (3.77) |
| Cholesterol | 0.04 (0.02)* | 0.04 (0.02)* | 0.04 (0.02)* | 0.03 (0.02) | 0.03 (0.02) | 0.03 (0.02) |
| LDL-C | 0.03 (0.01) | 0.03 (0.01) | 0.03 (0.01)* | 0.02 (0.01) | 0.02 (0.01) | 0.02 (0.01) |
| HDL-C | −0.11 (0.08) | −0.10 (0.08) | −0.04 (0.09) | −0.11 (0.08) | −0.10 (0.08) | −0.06 (0.09) |
| LDL-C/HDL-C | 0.27 (0.12)* | 0.26 (0.12)* | 0.22 (0.13) | 0.21 (0.12) | 0.22 (0.12) | 0.18 (0.13) |
| Triacylglycerol | 0.22 (0.09)* | 0.22 (0.09)* | 0.20 (0.10)* | 0.23 (0.09)* | 0.22 (0.09)* | 0.21 (0.10)* |
Data are unstandardised coefficients (B) (SEM)
Model 1: adjusted for age and sex
Model 2: model 1 with additional adjustment for marital status and SES (job status and manual occupation)
Model 3: model 2 further adjusted for smoking, alcohol, BMI and physical activity
*p < 0.05, **p < 0.01 and ***p = 0.001