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. 2015 Sep 14;153(3):583–590. doi: 10.1007/s10549-015-3562-5

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 1 — Tamoxifen metabolism. 4OHTam 4-hydroxytamoxifen, CYP cytochrome P450 isoenzyme, SULT sulfotransferase, UGT UDP-glucuronosyltransferase, NDMTam N-desmethyltamoxifen, NR1 nuclear receptor subfamily 1, PXR pregnane X receptor, CAR constitutive androstane receptor