Table 2.

Repeatability of [¹⁸F]HX4 uptake and hypoxic tumor volume and fraction using a threshold of 1.2 times background (HV_1.2)

Patient ID	SUVmean		SUVmax		TBRmax		HV1.2 (cm3)		FHV1.2 (%)
	Scan 1	Scan 2	Scan 1	Scan 2	Scan 1	Scan 2	Scan 1	Scan 2	Scan 1	Scan 2
Lung cancer
01	1.20	1.09	2.15	2.21	1.72	1.87	14.01	11.15	15.78	11.33
02	1.38	1.49	2.87	2.74	2.40	2.10	147.34	148.31	40.76	38.55
03	1.17	1.19	1.47	1.60	1.20	1.27	0.06	0.26	1.23	9.30
04	1.90	1.97	2.93	2.82	2.03	1.94	177.66	203.33	70.62	74.95
05	1.16	1.10	1.68	1.67	1.50	1.66	18.82	18.50	21.48	36.04
06	0.89	0.90	1.46	1.55	1.49	1.62	2.49	1.80	10.85	9.52
07	0.94	1.03	1.57	1.64	1.47	1.51	0.45	1.45	4.41	9.67
08	1.36	1.51	1.98	2.25	1.64	1.75	3.58	4.58	38.85	47.92
09	1.19	1.07	1.63	1.47	1.17	1.16	0.00	0.00	0.00	0.00
Mean ± SD	1.24 ± 0.29	1.26 ± 0.33	1.97 ± 0.57	1.99 ± 0.53	1.63 ± 0.39	1.65 ± 0.31	40.5 ± 69.9	43.3 ± 76.6	22.6 ± 23.4	26.4 ± 24.6
Head and neck cancer
10	0.91	0.92	1.25	1.29	1.04	1.01	0.00	0.00	0.00	0.00
11	0.89	0.99	1.23	1.31	1.04	1.08	0.00	0.00	0.00	0.00
12	1.85	1.72	2.52	2.39	1.32	1.27	3.90	1.54	4.89	2.02
13	1.09	0.97	1.30	1.15	1.17	1.09	0.00	0.00	0.00	0.00
14	1.15	0.99	1.71	1.37	1.42	1.28	0.90	0.13	5.04	0.67
15	1.17	1.12	1.72	1.80	1.44	1.69	3.65	5.57	11.56	20.57
16	0.98	1.05	1.77	1.96	1.79	2.08	1.01	2.03	14.55	33.83
17	1.23	1.17	2.48	2.33	3.35	3.15	211.24	203.71	85.14	80.03
18	1.15	1.18	1.49	1.39	1.36	1.23	0.60	0.27	11.33	5.11
19	1.26	1.28	2.12	2.05	1.96	1.99	28.73	41.24	42.07	57.56
Mean ± SD	1.17 ± 0.27	1.14 ± 0.23	1.76 ± 0.48	1.70 ± 0.46	1.59 ± 0.69	1.59 ± 0.67	25.0 ± 66.0	25.5 ± 63.9	17.5 ± 26.9	20.0 ± 28.5
Mean ± SD (total)	1.20 ± 0.28	1.20 ± 0.28	1.86 ± 0.52	1.84 ± 0.50	1.61 ± 0.55	1.62 ± 0.52	32.3 ± 66.4	33.9 ± 68.8	19.9 ± 24.7	23.0 ± 26.2