TABLE 1.
Summary of metabolomics dataa
| Genotypes | No. of biomolecule changesb |
|
|---|---|---|
| Total | Up/down | |
| WT vs STAT3−/− | 155 | 77/78 |
| STAT3−/− vs MTS | 48 | 19/29 |
a
Summary of the number of biomolecules with significantly altered abundance between different H-RasG12V-transformed cells.
b
The numbers of biomolecules changing between STAT3 wild-type (WT) and STAT3−/− MEFs and between WT and mitochondrially restricted STAT3 (MTS) MEFs are shown, including a breakdown of those whose abundance increased (up) or decreased (down). Relative abundance was determined from 6 independent replicates, and statistical significance was calculated by Welch's t test (P < 0.05).