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. 2015 Sep 30;35(21):3714–3725. doi: 10.1128/MCB.00298-15

FIG 7.

FIG 7

Potential impact of dynamic acetylation in regulation of gene expression upon DNA damage. (A) Wild-type and esa1 hos2Δ strains would maintain dynamic acetylation compared to esa1 and hos2Δ strains that have impaired dynamics. Acetylation is depicted by green circles on histone tails. (B) HOS2 deletion could not suppress esa1 in the absence of RPD3. Wild-type (LPY6497), esa1-531 (LPY14757), esa1-531 hos2Δ (LPY14761), esa1-531 hos2Δ rpd3Δ (LPY21428), esa1-531 rpd3Δ (LPY21450), and hos2Δ rpd3Δ (LPY21426) strains were plated on the indicated medium. (C) HOS2 deletion could not suppress esa1 in the absence of GCN5. Wild-type (LPY5), esa1-414 (LPY21400), esa1-414 hos2Δ (LPY21401), esa1-414 hos2Δ gcn5Δ (LPY21468), and gcn5Δ hos2Δ (LPY21399) strains were plated as indicated. The esa1-414 gcn5Δ strain was not included in the plating, as it was lethal when having esa1-414 expressed from a plasmid in the W303 background.