Table 2. The genotype and allele frequencies of the pri-miR-124 rs531564 polymorphism in CRC patients and controls.

Model comparison	Genotype/allele	Cases, n (%)	Controls, n (%)	OR (95% CI)	P-value
Co-dominant model	Xuzhou population	n = 577	n = 690
	CC	446 (77.3)	492 (71.3)	Reference
	CG	126 (21.8)	176 (25.5)	0.79 (0.61–1.02)	0.07
	GG	5 (0.9)	22 (3.2)	0.25 (0.09–0.67)	0.003
Dominant model	CC	446 (77.3)	492 (71.3)	Reference
	CG+GG	131 (22.7)	198 (28.7)	0.73 (0.56–0.94)	0.01
Recessive model	CC+CG	572 (99.1)	668 (96.8)	Reference
	GG	5 (0.9)	22 (3.2)	0.27 (0.10–0.70)	0.004
Allele model	C	1018 (88.2)	1160 (84.1)	Reference
	G	136 (11.8)	220 (15.9)	0.70 (0.56–0.89)	0.003
	Bengbu population	n = 323	n = 420
Co-dominant model	CC	247 (76.5)	298 (71.0)	Reference
	CG	74 (22.9)	110 (26.2)	0.81 (0.58–1.14)	0.22
	GG	2 (0.6)	12 (2.9)	0.20 (0.04–0.90)	0.02
Dominant model	CC	247 (76.5)	298 (71.0)	Reference
	CG+GG	76 (23.5)	122 (29.0)	0.75 (0.54–1.04)	0.09
Recessive model	CC+CG	321 (99.4)	408 (97.1)	Reference
	GG	2 (0.6)	12 (2.9)	0.21 (0.05–0.95)	0.03
Allele model	C	568 (87.9)	706 (84.0)	Reference
	G	78 (12.1)	134 (16.0)	0.72 (0.54–0.98)	0.03
	Pooled population	n = 900	n = 1110
Co-dominant model	CC	693 (77.0)	790 (71.2)	Reference
	CG	200 (22.2)	286 (25.8)	0.81 (0.66–1.00)	0.05
	GG	7 (0.8)	34 (3.1)	0.26 (0.11–0.59)	<0.001
Dominant model	CC	693 (77.0)	790 (71.2)	Reference
	CG+GG	207 (23.0)	320 (28.8)	0.76 (0.62–0.93)	0.008
Recessive model	CC+CG	893 (99.2)	1076 (96.9)	Reference
	GG	7 (0.8)	34 (3.1)	0.27 (0.12–0.62)	<0.001
Allele model	C	1586 (88.1)	1866 (84.1)	Reference
	G	214 (11.9)	354 (15.9)	0.71 (0.59–0.85)	<0.001