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. 2015 Oct 1;5:14699. doi: 10.1038/srep14699

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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We divided the genome into 1-kb non-overlapping windows and calculated average 5 mC level, RPM value and CpG density for each window. We classified the windows into 18 groups according to CpG density and we compared (A) the distribution of 5 mC levels and (B) the distribution of RPM values among these groups.