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. 2015 Oct 1;5:14699. doi: 10.1038/srep14699

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(A) Correlation analysis of MeSiC predictions and MEDIPS-normalized ams relative to 5 mC levels at different genomic elements on 24 chromosomes of the H1 cell line. Correlation analysis of MeSiC predictions and MEDIPS-normalized ams relative to BS-seq values at different genomic elements on 24 chromosomes of (B) BGMs and (C) NCCs. The ams which corrects for the CpG density of the element was calculated through dividing mean rms by mean coupling factors of bins that located in the element. (D) Concordance and (E) correlation analysis of the predictions of MeSiC and methylCRF relative to 5 mC levels at different genomic elements on 24 chromosomes of the H1 cell line. Solid and dash lines represent MeSiC and methylCRF, respectively. Different colors represent different genomic elements.