Table 2.
List of the differentially expressed proteins which is only dysregulated in HCC with multiple lesions.
| Differentially expressed proteins | Gene | Fold change | Fold change |
|---|---|---|---|
| MC/MN | SC/SN | ||
| UTP-glucose-1-phosphate uridylyltransferase | UGP2 | 0.62 | 0.68 |
| Bile acyl-CoA synthetase | SLC27A5 | 0.58 | 0.67 |
| Cytochrome P450 2A6 | CYP2A6 | 0.6 | 0.73 |
| Glycine dehydrogenase (decarboxylating), mitochondrial | GLDC | 0.65 | 0.72 |
| 17-Beta-hydroxysteroid dehydrogenase 13 | HSD17B13 | 0.56 | 0.71 |
| Glycogen [starch] synthase, liver | GYS2 | 0.65 | 0.7 |
| Sequestome-1 | SQSTM1 | 1.77 | 1.59 |
| 4-Hydroxyphenylpyruvate dioxygenase | HPD | 0.63 | 0.76 |
| Kynurenine 3-monooxygenase | KMO | 0.56 | 0.76 |
| Beta-enolase | ENO3 | 0.64 | 0.71 |
| Urocanate hydratase | UROC1 | 0.66 | 0.76 |
| Keratin, type I cytkeletal 20 | KRT20 | 1.53 | 1.97 |
| Synembryn-A | RIC8A | 1.56 | 1.4 |
| Cadherin-related family member 2 | CDHR2 | 0.64 | 0.78 |
| Cytochrome P450 2B6 | CYP2B6 | 0.64 | 0.69 |
| NAD(P)H dehydrogenase [quinone] 1 | NQO1 | 1.89 | 1.52 |
| Anterior gradient protein 2 homolog | AGR2 | 1.71 | 1.14 |
| Peripherin | PRPH | 0.64 | 0.7 |
| Fuce mutarotase | FUOM | 0.6 | 0.61 |
| Coiled-coil domain-containing protein 57 | CCDC57 | 1.54 | 1.4 |
| Gangliide-induced differentiation-associated protein 1 | GDAP1 | 1.51 | 1.44 |
| Histone H1.1 | HIST1H1A | 1.62 | 1.12 |
| Choline transporter-like protein 2 | SLC44A2 | 0.65 | 0.63 |
| RAS protein activator like-3 | RASAL3 | 0.63 | 0.79 |
| Non-histone chromomal protein HMG-17 | HMGN2 | 3.06 | 1.65 |
| FH1/FH2 domain-containing protein 1 | FHOD1 | 1.66 | 1.44 |
| Copine-6 | CPNE6 | 0.58 | 0.78 |
| Myeloblastin | PRTN3 | 1.51 | 1.94 |
| 24-Hydroxycholesterol 7-alpha-hydroxylase | CYP39A1 | 0.61 | 0.71 |
| Sodium/hydrogen exchanger 10 | SLC9C1 | 0.63 | 0.68 |
| Steroid 17-alpha-hydroxylase/17,20 lyase | CYP17A1 | 1.57 | 2.15 |
| HLA class I histocompatibility antigen, alpha chain G | HLA-G | 0.66 | 1.08 |
| MICAL C-terminal-like protein | MICALCL | 0.49 | 0.4 |
| Nucleolysin TIA-1 isoform p40 | TIA1 | 0.66 | 0.91 |
| Immunoglobulin-binding protein 1 | IGBP1 | 1.57 | 1.63 |
| Protein FAM171A1 | FAM171A1 | 0.59 | 0.63 |