Table 2.
Effect of topical application of the ointment formulated from 80 % methanol extract of the rhizomes of Rumex abyssinicus on wound contraction of excision wound model in mice
| Group | Wound area (mm2) on post-wounding days | ||||||
|---|---|---|---|---|---|---|---|
| 3 | 5 | 7 | 9 | 11 | 13 | 15 | |
| SO | 234.2 ± 11.8 | 202.0 ± 10.6 | 159.1 ± 13.0 | 110.0 ± 8.5 | 33.5 ± 5 | 20.5 ± 2.7 | 9.2 ± 3.0 |
| 5 % HEO | 179.3 ± 23.3 | 150 ± 15.0 | 80.2 ± 21.7a2 | 27.3 ± 11.4a2 | 10 ± 6a2 | 2 ± 1.4a3 | 0a2 |
| 10 % HEO | 82.4 ± 8.1 a3,c2 | 72.67 ± 9.2a3,c2 | 39.1 ± 8.1a3 | 11.0 ± 3.0a3 | 1.8 ± .5a3 | 0a3 | - |
| NFO | 130.7 ± 17.0a2 | 108.5 ± 17.4a3 | 54.5 ± 10.7a3 | 17.2 ± 4.8a3 | 4.8 ± 2a3 | 1.67 ± 1.3a3 | 0a2 |
n = 6 animals in each group; Values are expressed as mean ± SEM and analyzed by one way ANOVA followed by tuckey post hoc test; SO, simple ointment base; HEO, hydroalcoholic extract ointment; NFO, nitrofurazone ointment;.numbers (3-15) refer days where measurment was taken following wound creation; 0 values refer day where complete healing was achieved; aagainst control, cagainst 5 % (w/w) hydroalcoholic extract; 2 p < 0.01, 3 p < 0.001