Table 5.
Effect of topical application of the ointment formulated from 80 % methanol extract of the rhizomes of Rumex abyssinicus on tensile strength of incision wound
| Group | Tensile strength (g) (mean ± SEM) | % Tensile strength |
|---|---|---|
| Untreated control | 205.4 ± 19.5 | - |
| SO | 244.67 ± 17.1 | 19.4 % |
| 5 % HEO | 333.33 ± 18.2a1 | 36.2 % |
| 10 % HEO | 384.50 ± 19.6a3 | 57.2 % |
| NFO | 438.17 ± 19.1c2,a3 | 79.1 % |
n = 6 animals in each group; Values are expressed as mean ± SEM and analyzed by one way ANOVA followed by tuckey post hoc test; tensile strength was measured on the 10th post-wounding day using continuous water flow technique; SO, simple ointment base; HEO, hydroalcoholic extract ointment; NFO, nitrofurazone ointment; aagainst control treated with simple ointment base;c against 5% (w/w) hydroalcoholic extract;1 p < 0.05, 2 p < 0.01, 3 p < 0.001