Table 1.
Univariate analysis of factors correlated with overall survival of HCC patients
| Clinical variables | Case number | HR (95% CI) | p value |
|---|---|---|---|
| miR-197 (lower vs. higher) | 45/45 | 0.49 (0.27–0.90) | 0.0209 |
| IL6 (lower vs. higher) | 45/45 | 2.24 (1.22–4.11) | 0.0092 |
| STAT3 (lower vs. higher) | 45/45 | 1.881 (1.037–3.41) | 0.0375 |
| Sex (male vs. female) | 77/13 | 1.054 (0.45–2.49) | 0.9040 |
| Age (> 55 y vs. ≤ 55 y) | 42/48 | 0.997 (0.55–1.80) | 0.9910 |
| Cirrhosis (yes vs. no) | 32/58 | 0.782 (0.415–1.472) | 0.4460 |
| Tumor size (≥5 cm vs. <5 cm) | 54/36 | 2.087 (1.092–3.992) | 0.0261 |
| Tumor number (>1 vs. 1) | 9/81 | 1.97 (0.879–4.418) | 0.0998 |
| TNM stage (III/IV vs. I/II) | 47/43 | 2.65 (1.40–5.01) | 0.0029 |
| Histological grade (>II vs. I/II) | 36/54 | 1.281 (0.748–2.196) | 0.3670 |
CI: confidence interval; TNM: tumor-node-metastasis staging system.