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. 2015 Aug;10(8):1239–1244. doi: 10.4103/1673-5374.162755

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Copyright: © Neural Regeneration Research

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Effect of atorvastatin on brain infarct volume of rats with cerebral ischemia/reperfusion injury.

(A–D) Infarct volume was measured by TTC staining: normal brain tissue was red and infarcted tissue was white. (A) Sham group; (B) ischemia/reperfus group; (C) atorvastatin group; (D) atorvastatin + salubrinal group. (E) Quantitative analysis of brain infarct volume in the rat brain. Data are represented as the mean ± SD (n = 15 rats in each group). The differences among groups were compared with one-way analysis of variance followed by the least significant difference test. *P < 0.05, vs. I; #P < 0.05, vs. II. I: Sham group; II: ischemia/reperfusion group; III: atorvastatin group; IV: atorvastatin + salubrinal group.