Figure 2.

Effect of atorvastatin on the ultrastructure of neurons in infarcted brain tissue of rats with cerebral ischemia/reperfusion injury (transmission electron microscopy, × 20,000).

Neuronal damage was most obvious in the ischemia/reperfusion group, showing the swelling, vacuoles and debris of mitochondria, Golgi complex and endoplasmic reticulum (arrows), unclear or disappeared mitochondria, and nuclear enrichment. (A) Sham group; (B) ischemia/reperfusion group; (C) atorvastatin + salubrinal group; (D) atorvastatin group.