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. 2015 Aug;10(8):1265–1270. doi: 10.4103/1673-5374.162759

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Copyright: © Neural Regeneration Research

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Effects of blocking EPO on cell proliferation in the SVZ of rats with ischemic injury after treatment with hBMSCs.

(A–C) Newborn cells in the SVZ of rats at 14 days after injury. BrdU-positive cells are brown. (A) Heat-denatured sEPOR group; (B) hBMSCs + heat-denatured sEPOR group; (C) hBMSCs + sEPOR group. Scale bar: 20 μm. (D) Number of BrdU-labeled cells in the SVZ. Data are expressed as the mean ± SD (six rats in each group). §P < 0.05, vs. hBMSCs + heat-denatured sEPOR group (one-way analysis of variance). tMCAo: Transient middle cerebral artery occlusion; sEPOR: soluble erythropoietin receptor; SVZ: subventricular zone.