Table 3.
Lung function parameters, ACT, CAT, and mMRC tests of patients with asthma, COPD, and ACOS
| Asthma | ACOS | COPD |
P-value
|
||
|---|---|---|---|---|---|
| Asthma vs ACOS | COPD vs ACOS | ||||
| FEV1 (% pred) | 87.61±2.70 | 56.25±4.26 | 32.67±3.93 | <0.0001 | <0.0001 |
| FVC (% pred) | 98.34±2.43 | 77.15±3.42 | 56.05±3.69 | <0.0001 | 0.0002 |
| FEF25–75 (% pred) | 63.49±3.95 | 28.85±3.51 | 13.76±1.26 | <0.0001 | 0.0002 |
| PEF (% pred) | 83.41±3.09 | 48.75±3.87 | 28.86±2.12 | <0.0001 | <0.0001 |
| Raw (% pred) | 150.6±9.08 | 171.1±20.95 | 267.9±20.27 | 0.29 | 0.0024 |
| mMRC total score, mean [range] | – | 1.80 [1–3] | 3.57 [2–4] | – | <0.0001 |
| ACT total score, mean [range] | 20.95 [9–25] | 15.60 [8–24] | – | <0.0001 | – |
| CAT total score, mean [range] | – | 17.95 [6–30] | 21.14 [12–31] | – | 0.11 |
Notes: Data expressed as mean ± SEM if not stated otherwise. Significant differences are highlighted in bold.
Abbreviations: ACOS, asthma–COPD overlap syndrome; ACT, asthma control test; CAT, COPD assessment test; COPD, chronic obstructive pulmonary disease; FEF25–75, forced expiratory flow between 25% and 75% of FVC; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; mMRC, modified Medical Research Council; % pred, % predicted; Raw, airway resistance; SEM, standard error of mean.