Table S1.
Effects of PLGA nanoparticles on cytokine secretion
| PLGA (µg/mL) |
IL-1β (pg/mL) |
IL-6 (pg/mL) |
IL-10 (pg/mL) |
TNF-α (pg/mL) |
|---|---|---|---|---|
| 0 | 9.57 | <0.20 | <0.5 | <0.40 |
| 2 | 7.88 | <0.20 | 0.79 | 0.72 |
| 200 | 7.31 | <0.20 | 1.07 | <0.40 |
| 400 | 21.77 | 0.33 | 1.36 | 1.7 |
Notes: THP-1 monocyte-derived macrophages were exposed to PLGA nanoparticles for 48 hours and cytokine secretion was measured in supernatants by the luminex multiplex bead assay. Data represent value of pooled triplicates from one experiment.
Abbreviations: PLGA, poly(lactic-co-glycolic) acid; IL, Interleukin; TNF, tumor necrosis factor.