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Simulated time course of T. cruzi in colonies of T. infestans. Simulations tracked 1000 vectors and a host population of 10 guinea pigs that declined to two hosts during bottleneck periods. A total of 1000 replicate simulations were run for each bottleneck length. (a) No bottleneck. (b–f) Bottleneck durations of 14, 30, 60, 90 and 180 days, respectively. Solid vertical lines indicate the start of the bottleneck, and dashed vertical lines indicate the end.
