Table S1.

The search strategy of PubMed

No	Query results	Results
14	Search ((((((((coronary heart disease[Text Word]) OR ischemic heart disease[Text Word]) OR angina pectori[Text Word]) OR angina[Text Word]) OR acute coronary syndrome[Text Word]) OR myocardial infarction[Text Word]) OR myocardial infarct[Text Word]) OR coronary artery disease[MeSH]) AND ((tumor necrosis factor[Text Word]) OR TNF[Text Word]) AND polymorphism[Text Word]	159
13	Search polymorphism[Text Word]	229,416
12	Search (tumor necrosis factor[Text Word]) OR TNF[Text Word]	167,359
11	Search TNF[Text Word]	113,071
10	Search tumor necrosis factor[Text Word]	136,792
9	Search (((((((coronary heart disease[Text Word]) OR ischemic heart disease[Text Word]) OR angina pectori[Text Word]) OR angina[Text Word]) OR acute coronary syndrome[Text Word]) OR myocardial infarction[Text Word]) OR myocardial infarct[Text Word]) OR coronary artery disease[MeSH]	304,794
8	Search Coronary Artery Disease[MeSH]	37,314
7	Search myocardial infarct[Text Word]	18,735
6	Search myocardial infarction[Text Word]	189,875
5	Search acute coronary syndrome[Text Word]	14,457
4	Search angina[Text Word]	60,634
3	Search angina pectori[Text Word]	0
2	Search ischemic heart disease[Text Word]	20,146
1	Search coronary heart disease[Text Word]	39,801