Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Sep 18;9:1731–1740. doi: 10.2147/OPTH.S87972

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 Lahooti et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

CASQ1 protein concentrations and CASQ1 antibody titer.

Notes: (A) Mean ± standard deviation, CASQ1 protein concentrations in thyroid tissues from patients having rs74123279 SNP with GH (61.56±18.32 pmol/mg), GO (81.44±43.98 pmol/mg) and as normal thyroid, from control patients with multinodular goiter or thyroid cancer (145.6±26.56 pmol/mg) determined from quantitative Western blotting. The difference between GH and controls and GO and controls was highly significant (Mann–Whitney test: *P=0.013 and *P=0.047, respectively). (B) Mean ± standard deviation, CASQ1 antibody titer in serum samples from patients having rs74123279 SNP that thyroid tissues were studied for measurement of CASQ1 protein concentrations with GH (305.1±45.65), GO (370.9±128.8), and as normal thyroid, from control patients with multinodular goiter or thyroid cancer (499.2±49.77) determined by enzyme-linked immunosorbent assay. The difference between GH and Controls was significant (Mann–Whitney test: *P=0.011), and GO and control failed to reach significance (Mann–Whitney test P=0.084).

Abbreviations: CASQ1, calsequestrin; SNP, single-nucleotide polymorphism; GH, Graves’ hyperthyroidism; GO, Graves’ ophthalmopathy; OD, optical density.