Table 5.
Minor and major alleles distribution of CASQ1 SNPs rs74123279, rs3747673, rs2275703 in patients with and without ophthalmopathy
| SNP | Graves’ ophthalmopathy group
|
||||
|---|---|---|---|---|---|
| Minor alleles (n) | Major alleles (n) | Chi-square | Odds ratio (95% confidence interval) | P-value | |
| rs74123279 | 35 | 113 | 2.447 | 1.51 (0.898–2.55) | 0.117 |
| Control group | 36 | 176 | |||
| rs3747673 | 54 | 98 | 0.950 | 0.807 (0.525–1.24) | 0.329 |
| Control group | 86 | 126 | |||
| rs2275703 | 79 | 67 | 6.91 | 1.77 (1.15–2.71) | 0.008 |
| Control group | 84 | 126 | |||
Abbreviations: CASQ1, calsequestrin; SNP, single-nucleotide polymorphism.