Table 3.
Comparison of demographics and clinical features of DF and DHF
| Overall Cases (N = 667) n (%) | DF (N = 588) n (%) | DHF (N = 79) n (%) | P–value* | |
|---|---|---|---|---|
| Age > 40 years | 167 (25) | 137 (23.3) | 30 (38) | 0.005 |
| Male gender | 378 (56.7) | 326 (55.4) | 52 (55.8) | 0.08 |
| Urban resident | 403 (60.4) | 346 (41.2) | 57 (72.2) | 0.023 |
| Temperature > 38 Co | 229 (34.3) | 197 (33.5) | 32 (40.5) | 0.218 |
| Obesity | 94 (14.1) | 82 (13.2) | 12 (15.2) | 0.467 |
| Co-morbidities | ||||
| DM | 36 (5.4) | 13 (2.2) | 23 (29.1) | 0.001 |
| HTN | 35 (5.2) | 17 (2.9) | 18 (22.4) | 0.021 |
| CKD | 33 (4.9) | 26 (4.4) | 7 (8.9) | 0.085 |
| IHD | 25 (3.7) | 19 (3.2) | 6 (7.6) | 0.178 |
| CHF | 2 (0.3) | 2 (0.3) | 0 (0) | - |
| HPL | 8 (1.2) | 7 (1.2) | 1 (1.3) | 0.649 |
| Risk group associationa | 264 (39.6) | 232 (39.5) | 32 (40.5) | 0.858 |
| Secondary infection | 73 (10.9) | 58 (9.9) | 18 (22.8) | 0.015 |
| Warning signs | 271 (40.6) | 224 (38.1) | 47 (59.7) | 0.000 |
| Positive Hess test | 101 (15.1) | 85 (14.5) | 16 (20.3) | 0.177 |
| Low MAP | 37 (5.5) | 34 (5.8) | 3 (3.8) | 0.469 |
| Elevate Scr (AKI) | 95 (14.2) | 58 (9.9) | 37 (65.8) | 0.000 |
| Thrombocytopenia | 395 (59.2) | 343 (58.3) | 56 (70.8) | 0.042 |
| Leukopenia | 363 (54.4) | 321 (54.6) | 42 (53.2) | 0.596 |
| Leukocytosis | 36 (5.4) | 32 (5.4) | 4 (5.1) | 0.842 |
| Elevated ALT | 362 (54.3) | 315 (53.6) | 47 (59.5) | 0.321 |
| Elevated AST | 447 (67) | 380 (64.6) | 67 (84.8) | 0.000 |
| Elevated ALP | 113 (19.9) | 117 (19.9) | 16 (20.3) | 0.885 |
| Transaminitis | 360 (54) | 311 (52.9) | 49 (62) | 0.125 |
| Rhabdomyolosis | 49 (7.3) | 34 (5.8) | 15 (19) | 0.000 |
| Multiple organ dysfunctions | 138 (20.7) | 97 (16.5) | 43 (54.4) | 0.000 |
| Urinary sedimentations | 96 (14.4) | 78 (13.3) | 18 (22.8) | 0.034 |
| Hemoconcentration | 73 (10.9) | 56 (9.5) | 17 (21.5) | 0.001 |
| Prolonged PT and aPTT | 116 (17.4) | 93 (15.6) | 23 (29.1) | 0.003 |
| Delayed Hospitalization (>3 days of onset of illness) | 153 (22.9) | 105 (17.9 %) | 48 (60.8) | 0.000 |
| Death | 8 (1.2) | 6 (1) | 2 (2.5) | 0.243 |
*Chi-Square/Fisher’s Exact test, where appropriate, adefined as number of patients having association of dengue infection risk groups as described under results section