Table 1.
Pharmaceutical applications of proliposomal formulations in drug discovery and development with examples.
| Formulation | Drug | Developmental issues addressed | Reference |
|---|---|---|---|
| Proliposomes beads with DSPC | Glyburide | Dissolution | 63 |
| Proliposomes beads with DSPC | Halofrantine | Bioavailability | 64 |
| Proliposomal beads with DSPC, cholesterol and Tween 80 | Cromolyn sodium | Permeability | 65 |
| HSPC/cholesterol/stearylamine | Zaleplon | Bioavailability and first pass effect | 66 |
| Lipid formulation with phosphatidylcholine/cholesterol | Vinpocetine | Solubility limited bioavailability | 67 |
| Lipid formulation with phosphatidylcholine | Silymarin | Poor solubility in water/oils, poor bioavailability | 68 |