Table 6.

DTI measures of white matter tracts in HIV positive patients with history of psychostimulant use

	Controls (n = 22)	Patients (n = 20)	Effect size (d) and p value
Genu of CC
FA	0.3838 ± 0.0254	0.3517 ± 0.0289	1.184; 0.0001*
MD	0.910 ± 0.054	0.951 ± 0.039	−0.864; 0.008*
AD	1.283 ± 0.071	1.301 ± 0.047	−0.296; 0.324
RD	0.723 ± 0.052	0.775 ± 0.046	−1.056; 0.002*
Right ALIC
FA	0.3555 ± 0.0229	0.3391 ± 0.0233	0.710; 0.027*
MD	0.907 ± 0.064	0.953 ± 0.060	−0.740; 0.022*
AD	1.245 ± 0.071	1.288 ± 0.061	−0.647; 0.044*
RD	0.737 ± 0.064	0.785 ± 0.063	−0.756; 0.020*
Left ALIC
FA	0.3798 ± 0.0307	0.3539 ± 0.0190	1.002; 0.002*
MD	0.857 ± 0.055	0.914 ± 0.042	−1.157; 0.001*
AD	1.208 ± 0.061	1.254 ± 0.049	−0.827; 0.011*
RD	0.681 ± 0.058	0.745 ± 0.042	−1.254; 0.0001*
AC
FA	0.3782 ± 0.0499	0.3509 ± 0.0332	0.638; 0.042*
MD	1.107 ± 0.189	1.142 ± 0.200	−0.180; 0.558
AD	1.539 ± 0.187	1.555 ± 0.239	−0.075; 0.773
RD	0.937 ± 0.184	0.893 ± 0.191	0.235; 0.455

Numbers indicate mean score (±SEM) for fractional anisotropy (FA), medial diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD) values for either the patient or control group; units for MD, AD and RD are (mm²/s × 10⁻³). Tracts include the genu of the corpus callosum (CC), left and right anterior limb of the internal capsule (ALIC) and the anterior commissure (AC). Values represent group mean ± SD

* Significant difference between groups p < 0.05