Table 2.
Three-point flexural properties of femurs in Pb-treated and diet-fed mice after 12 weeks on diet.
| Treatment | Stiffness (n/mm) | Modulus (MPa) | Max force (n) | Max stress (MPa) | Toughness (mJ/mm3) | Post-yield strain (%) |
|---|---|---|---|---|---|---|
| LFD | 75.5 ± 4.7 | 4,293 ± 488 | 16.9 ± 0.8 | 121 ± 8 | 4.49 ± 0.29 | 3.30 ± 0.13 |
| HFD | 70.7 ± 5.1 | 3,902 ± 558 | 15.2 ± 1.2 | 128 ± 16 | 4.62 ± 0.55 | 3.28 ± 0.18 |
| 50 ppm Pb + LFD | 52.9 ± 6.1a | 3,981 ± 603 | 14.6 ± 0.6a | 131 ± 8 | 4.66 ± 0.50 | 2.68 ± 0.13a |
| 50 ppm Pb + HFD | 66.6 ± 2.3a | 3,989 ± 146 | 14.9 ± 0.7a | 117 ± 8 | 3.61 ± 0.33 | 2.26 ± 0.25a |
| Data are mean ± SEM (n = 6/group). ap < 0.05 for effect of Pb exposure by two-way ANOVA. | ||||||