Table 4.
The crude and adjusted least square means (LSMs) and regression coefficients (β) for the birth weight (g) of male and female infants by quartiles of PFOS.
| PFOS in quartiles (ng/mL) | Crude | Adjusteda | ||
|---|---|---|---|---|
| LSM | β (95% CI) | LSM | β (95% CI) | |
| Male infants (n = 141) | ||||
| Quartile 1 (1.60–4.35) | 3059.5 | Reference | 3069.2 | Reference |
| Quartile 2 (4.35–5.80) | 3010.6 | –48.9 (–267.6, 169.8) | 3012.4 | –56.7 (–255.9, 142.4) |
| Quartile 3 (5.80–7.45) | 3151.3 | 91.7 (–123.3, 306.8) | 3099.7 | 30.5 (–169.7, 230.8) |
| Quartile 4 (7.45–16.20) | 3144.1 | 84.5 (–136.9, 306.0) | 3165.1 | 95.9 (–116.5, 308.4) |
| p for trend | 0.182 | 0.187 | ||
| Female infants (n = 165) | ||||
| Quartile 1 (1.50–3.80) | 3147.0 | Reference | 3125.4 | Reference |
| Quartile 2 (3.80–5.50) | 3034.6 | –112.4 (–310.5, 85.6) | 3055.2 | –70.1 (–242.5, 102.2) |
| Quartile 3 (5.50–7.65) | 3120.1 | –26.9 (–217.7, 163.9) | 3086.3 | –39.1 (–216.1, 137.8) |
| Quartile 4 (7.65–13.30) | 2934.6 | –212.3 (–400.7, –24.0)* | –186.6 (–363.4, –9.8)* | |
| p for trend | 0.030 | 0.031 | ||
| aAdjusted for gestational age, maternal age, prepregnancy BMI, smoking and drinking during pregnancy, parity, annual household income, and blood sampling period (categorical). *p < 0.05 compared with quartile 1 calculated by Hsu–Dunnett method. | ||||