Fig. 1.
Reduced spontaneous neuromuscular synaptic activity in UCH-L1−/− mice. Sample traces of mEPPs from wild-type (WT, +/+) and UCH-L1−/− mice at 1.5-, 2-, 3-, and 5 months of age: each trace is a set of 20 superimposed 200 ms-sweeps representing a 4-s continuous recording from an individual muscle fiber. MEPP frequencies are reduced in UCH-L1−/− mice after 2 months of age, compared with age-matched WT mice (modified from ref. 15).