Table 1.
Liquid filling formulations of VAL.
| Ingredients (mg/cap) | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Valsartan | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 | 40 |
| PVP K 30 | — | — | — | — | 10 | 10 | 20 | — | 10 | 10 | 20 |
| PEG 400 | 100 | 100 | 160 | 130 | 120 | 120 | 110 | 130 | 120 | 120 | 110 |
| PG | 40 | 20 | — | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 |
| BHT | — | — | — | — | — | — | — | — | — | 1.0 | 1.0 |
| SBS | — | — | — | — | — | 0.1 | 0.1 | — | — | — | — |
| Water | 20 | 40 | — | 20 | 20 | 20 | 20 | — | — | — | — |
| Ethanol | — | — | — | — | — | — | — | 20 | 20 | 20 | 20 |
|
| |||||||||||
| Total weight | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 | 200 |
PVP K 30: polyvinylpyrrolidone; PEG 400: polyethylene glycol; PG: propylene glycol; BHT: butylated hydroxy toluene; SBS: sodium meta bisulfite.