Table 1.
Composition of indomethacin-loaded SNEDDS based on goat fat only.
| Batch | Ratio∗ O : S : CS | Goat fat (g) | Tween 65 (g) | Tween 80 (g) | Span 85 (g) | Carbosil (mg) | Indomethacin (mg) |
|---|---|---|---|---|---|---|---|
| 1A | 20 : 60 : 20 | 0.8 | 1.2 | 1.2 | 0.8 | — | 400 |
| 1B | 20 : 60 : 20 | 0.8 | 1.2 | 1.2 | 0.8 | 300 | 400 |
| 2A | 35 : 45 : 20 | 1.4 | 0.9 | 0.9 | 0.8 | — | 400 |
| 2B | 35 : 45 : 20 | 1.4 | 0.9 | 0.9 | 0.8 | 300 | 400 |
| 3A | 25 : 55 : 20 | 1.0 | 1.1 | 1.1 | 0.8 | — | 400 |
| 3B | 25 : 55 : 20 | 1.0 | 1.1 | 1.1 | 0.8 | 300 | 400 |
| 4A | 25 : 60 : 15 | 1.0 | 1.2 | 1.2 | 0.8 | — | 400 |
| 4B | 25 : 60 : 15 | 1.0 | 1.2 | 1.2 | 0.8 | 300 | 400 |
*Ratio of oil (goat fat) : surfactant blend (Tween 65 and Tween 80) : cosurfactant (Span 85).