Table 4.
Absolute drug contents of indomethacin-loaded SNEDDS.
| Batch∗ | Ratio of oil blend : surfactant blend : cosurfactant | Absolute drug contents (mg)∗∗ ± SD |
|---|---|---|
| 1A | 20 : 60 : 20 | 15.34 ± 0.96 |
| 1B | 20 : 60 : 20 | 16.60 ± 1.28 |
| 1C | 20 : 60 : 20 | 16.70 ± 1.09 |
| 1D | 20 : 60 : 20 | 19.36 ± 1.83 |
| 2A | 35 : 45 : 20 | 15.18 ± 1.07 |
| 2B | 35 : 45 : 20 | 17.40 ± 0.84 |
| 2C | 35 : 45 : 20 | 18.10 ± 0.53 |
| 2D | 35 : 45 : 20 | 19.05 ± 1.91 |
| 3A | 25 : 55 : 20 | 17.30 ± 0.82 |
| 3B | 25 : 55 : 20 | 18.50 ± 1.65 |
| 3C | 25 : 55 : 20 | 15.47 ± 1.26 |
| 3D | 25 : 55 : 20 | 19.60 ± 0.99 |
| 4A | 25 : 60 : 15 | 18.10 ± 0.74 |
| 4B | 25 : 60 : 15 | 19.60 ± 1.58 |
| 4C | 25 : 60 : 15 | 19.30 ± 1.92 |
| 4D | 25 : 60 : 15 | 18.41 ± 1.87 |
*A contains goat fat, B contains goat fat and carbosil, C contains goat fat with melon oil, and D contains goat fat with melon oil and carbosil. ∗∗All batches were intended to deliver 20 mg of indomethacin.