Table 2.
Haemogram and renal function tests in control and Rhubarb groups before and after 12 weeks of treatment.
| Serial number | Parameter | Group | 0 week mean ± SD |
12 weeks mean ± SD |
% change after 12 weeks | 95% confidence interval |
|---|---|---|---|---|---|---|
| 1 | Hb% (g/dL) |
I | 7.91 ± 1.93 | 8.91 ± 1.48c | (+) 12.64% | (−) 1.24 to (−) 0.75 |
| II | 7.87 ± 2.06 | 9.05 ± 1.58c1 | (+) 14.99% | (−) 1.51 to (−) 0.85 | ||
|
| ||||||
| 2 | FBG (mg/dL) |
I | 130.05 ± 42.90 | 113.78 ± 14.31c | (−) 12.51% | 8.88 to 23.64 |
| II | 132.60 ± 45.55 | 107.20 ± 18.03c2 | (−) 19.15% | 14.97 to 35.82 | ||
|
| ||||||
| 3 | PPBG (mg/dL) |
I | 184.95 ± 61.17 | 157.56 ± 23.20c | (−) 14.80% | 17.38 to 37.40 |
| II | 182.30 ± 62.05 | 147.65 ± 15.46c2 | (−) 19.00% | 23.17 to 46.11 | ||
|
| ||||||
| 4 | B. Urea (mg/dL) |
I | 107.16 ± 35.85 | 79.78 ± 24.79b | (−) 25.55% | 21.83 to 32.92 |
| II | 108.89 ± 42.65 | 72.25 ± 20.89c1 | (−) 33.64% | 30.97 to 42.30 | ||
|
| ||||||
| 5 | S.Cr. (mg/dL) |
I | 4.44 ± 1.64 | 3.33 ± 1.37c | (−) 25.00% | 0.86 to 1.37 |
| II | 4.06 ± 2.08 | 2.82 ± 1.11 c1 | (−) 30.54% | 0.91 to 1.55 | ||
|
| ||||||
| 6 | K+
(mEq/L) |
I | 4.87 ± 0.49 | 4.63 ± 0.41a | (−) 4.92% | 0.27 to 0.41 |
| II | 4.84 ± 0.44 | 4.42 ± 0.48b2 | (−) 8.67% | 0.26 to 0.57 | ||
|
| ||||||
| 7 | Ca2+
(mg/dL) |
I | 8.65 ± 1.05 | 8.89 ± 1.00a | (+) 2.77% | (−) 0.53 to 0.07 |
| II | 8.72 ± 1.01 | 9.38 ± 0.90b2 | (+) 7.56% | (−) 0.93 to (−) 0.38 | ||
|
| ||||||
| 8 | TUP (g/day) |
I | 3.03 ± 1.29 | 2.43 ± 0.97b | (−) 19.80% | 0.35 to 0.85 |
| II | 3.18 ± 1.57 | 2.12 ± 0.65c1 | (−) 30.18% | 0.83 to 1.09 | ||
|
| ||||||
| 9 | TUV (mL/day) |
I | 1454.36 ± 221.53 | 1736.76 ± 176.04c | (+) 19.41% | (−) 333.40 to (−) 230.38 |
| II | 1451.69 ± 303.74 | 1870.14 ± 258.78c3 | (+) 28.82% | (−) 467.28 to (−) 369.61 | ||
|
| ||||||
| 10 | GFR (mL/min) |
I | 19.0 ± 1.17 | 23.3 ± 1.63b | (+) 22.6% | 5.28 to 9.73 |
| II | 19.1 ± 2.37 | 28.0 ± 3.51c3 | (+) 46.5% | 5.99 to 15.31 | ||
Values are mean ± SD; P < 0.05 was considered significant; a P < 0.05, b P < 0.01, c P < 0.001 compared to 0 week value of respective group; 1 P < 0.05, 2 P < 0.01, 3 P < 0.001 compared to control group. I: control; II: Rhubarb; Hb%: haemoglobin percent; FBG: fasting blood glucose; PPBG: postprandial blood glucose; B. urea: blood urea; S.Cr.: serum creatinine; K+: serum potassium; Ca2+: serum calcium; TUP: 24 hour total urine protein; TUV: 24 hour total urine volume; GFR: glomerular filtration rate; (−) decrease; and (+) increase.