Table 1.
Examples of false claims made in drug advertisements.
1 | Tiapride | Claim | 61% improvement in cognitive impairment with tiapride as compared to 26.3% with quetiapine [19] |
Analysis | The claim was based on a referenced study which dealt with tiapride versus haloperidol and tiapride versus placebo in elderly patients with cognitive impairment and not quetiapine | ||
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2 | Combination of thiocolchicoside, aceclofenac, and paracetamol | Claim | Thiocolchicoside is safe and nonsedating muscle relaxant |
Analysis | (i) Primary adverse effects with thiocolchicoside include somnolence, vasovagal attack, and hepatic toxicity [20] (ii) There is no reference in support of this claim |
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3 | Rabeprazole plus diclofenac | Claim | Rabeprazole is ideal for prophylactic use in NSAIDS in high risk patients |
Analysis | (i) Lansoprazole has been recommended in high risk patients prone to ulcers and not rabeprazole [21, 22] (ii) Irretrievable reference |
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4 | Diclofenac | Claim | Lesser incidence of GI toxicity than nonselective NSAIDS such as indomethacin |
Analysis | GI symptoms are most common adverse effects observed with diclofenac with about 2% people withdrawing from treatment due to these side effects [23] |