US2008260700 |
Accili, Domenico; Kitamura, Tadahiro |
Established an immortalized pancreatic duct cell derived from a primary adult pancreatic duct epithelial cell culture, wherein the immortalized cell expresses wild type FoxO1 or mutated FoxO1; A method for treating beta cell failure with a subject spontaneously immortalized pancreatic ductal cell line expressing mutated FoxO1 |
US2008248995 |
Karnieli, Eddy; Armoni, Michal |
A method for detecting a modulator of transcription of a human PPAR gene promoter, wherein said FoxO1 protein binds directly and specifically through its DNA binding domain to a DNA region within the PPAR-gamma 2 promoter. A compound wherein the peptide is derived from the FoxO1 DNA-binding domain and some analog of said peptide. |
EP1907016 |
Cho, Charles; Chanda, Sumit |
A method for identifying modulating compounds that affect FoxO1 localization. |
US2008153767/WO2004031350 |
Dobie, Kenneth; Bhanot, Sanjay |
A series of antisense compounds, compositions are claimed for modulating the expression of FoxO1, a method for treatment of diseases associated with expression of FoxO1, in particular for treating diabetes |